Biological Engineering (BIOE)


This course introduces students to the fundamental concepts of Biological Engineering. Knowledge of thermodynamics and fluid mechanics is critical for students to solve biological engineering problems. Students will learn about energy, entropy and enthalpy in their various forms in a biological setting. Students will also learn basic fluid statics and dynamics. These topics will be applied in assignments, exams and in the laboratory to solve biomedical and biochemical engineering problems. Case studies are presented to allow student to put together their knowledge gained in these topics to solve problems pertaining to human organ systems like heart, lungs and kidneys. Prerequisites: CHEM1100 and ENGR1800; Corequisite: PHYS1750 (4 credits) fall


This course is intended for Biological Engineering students and introduces statistical models for analyzing data in the life and health sciences. The course examines descriptive statistics, probability, sampling, probability distributions, estimation, hypothesis testing, analysis of variance and other statistics models. Prerequisites: BIOL1100 and MATH1850 (4 credits) spring


Methods of using instrumentation for measurements in biological engineering are investigated in this course. Topics include the scientific method, sensors and physical phenomenon, data acquisition, analysis and statistics, and instruments for biological engineering. The laboratory exercises focus on the sensor interface, data acquisition, and development of software algorithms to analyze the data. Prerequisites: ENGR1800, BIOL1100 and BIOE2000; Corequisite: CHEM1600 (4 credits) spring


Introduction to fundamental principles and methods of microfluidics including capillarity, low Reynolds number flows, diffusion, osmosis, electrical fields, flow through porous media, microfabrication and lateral flow assays with an emphasis on global health diagnostic technologies. Fluid dynamics concepts for bulk flows both in physiological systems and in terms of microfluidic tools for exploring transport phenomena of single cells and tissue scale systems will be covered. Prerequisites: BIOE3025 (4 credits)


The chemical and mechanical properties of materials for biological systems are investigated. Cell culture, scaffolds and constructs for tissue engineering application are explored. Prerequisites: BIOE2000 and CHEM3550 (4 credits) summer


An engineering approach to microbiology and bio-based products. As bioengineering continues to grow as a discipline, biomanufacturing using "microbial cell factories" continues to pique the interests of the entrepreneur. Commodity compounds, from amino acids to biopolymers, can be manufactured fermentatively. With a growing list of organismal genome sequences available for analysis and manipulation, organisms ( mainly microorganisms) will be utilized and subsequently manipulated by the growing number of molecular biology and synthetic biology techniques available. Students will utilize the methods and concepts taught in this course for problem solving in biotechnology, biomanufacturing and the biopharmaceutical fields. This course discusses cellular and organismal metabolic networks and the mathematical and experimental manipulation of those networks. The techniques of synthetic biology and metabolic flux analysis, core concepts in metabolic engineering, are focused on here. Prerequisites: BIOL1000 and BIOE2000 (4 credits)


This course provides students with an introduction to the fundamental principles of molecular biotechnology and methodologies used for gene manipulation. The didactic portion of this course will cover topics including recombinant DNA technology and molecular cloning, bioinformatics, genome and protein engineering and transgenic plants and animals. The laboratory portion will introduce students to methods commonly used for gene manipulation studies including: cell culture, DNA isolation, restriction enzymes and mapping, cloning strategies, immunological screening of proteins and other essential techniques. Prerequisites: BIOL2200 (4 credits) fall


This course introduces fundamental design and operation principles of biological engineering systems, including bioreactors, phase transfer, separation and other mass transfer operations. (4 credits) summer


Introductions to concepts, techniques and programming skills for computational biology, including simulation and game theory. The system models include central control, multiple actor based, deterministic, stochastic, differential equations, and spatial representation and graphics (at least two dimensional). Prerequisites: MATH2500 and BIOE2500 (4 credits)


These courses present topics that are not covered by existing courses and are likely to change from semester to semester. Refer to the semester schedule for the courses offered that semester. Contact the faculty assigned for more information about the course topic. (1 - 4 credits)


This course focuses on intercellular communication via chemical, electrical and mechanical stimuli. Topics include membrane-bound and intracellular receptor proteins, cellular responses to receptor activation, membrane potentials, sensory receptors and the endocrine and nervous organ systems. Prerequisite: BIOL1100 (4 credits) spring


This course explores transport phenomena (momentum, heat, and mass transfer) as related to biological systems. This includes microscale and molecular processes for membrane transport and perfusion, such as diffusion, osmosis, passive and active transport, and electrophysiology. Dynamics of mechanical flow for fluid and heat are introduced for cells, tissues and organ systems. Prerequisites: BIOE2000, BIOE2500 and MATH2500 (4 credits) spring